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王金华

时间:2020/7/17 来源: 阅读:20962次


王金华

王金华博士,研究员,博士生导师,课题组长。中国医学科学院药物研究所引进人才(2015)。现任中国医学科学院药物研究所国家新药筛选中心副主任,实聘课题组长中国医学科学院药物研究所、北京协和医学院 协和学者特聘教授中国医学科学院医学与健康科技创新工程协同创新团队首席科学家,赣江创新人才。

 

 

 

教育背景:

1999.8 2004.6    硕、博连读,博士,北京大学

1991.8 1996.6    学士,首都医科大学

 

研究经历:

2015.3至今         中国医学科学院药物研究所、北京协和医学院研究员博士生导师

2013.2 2015.3    Assistant professor, faculty. John Wayne Cancer Institute, Los Angeles, CA90404 (美国)

2010.8 2013.1    Medical scientist, John Wayne Cancer Institute, Los Angeles, CA 90404. (美国)

2007.10 2010.7   Research Associate, Department of Molecular Oncology, John Wayne Cancer Institute. Los Angeles, CA 90404. (美国)

2006.7 2007.10   Research Associate, Department of Neuropathology, Case Western Reserve University, Cleveland, Ohio USA. (美国)

2004.6 2006.6    博士后,中国医学科学院、中国协和医科大学药物研究所

1996.8 1999.8    江西省人民医院

 

联系方式:

010-63165313  邮箱:wjh@imm.ac.cn

 

研究方向:

 

主要从事肿瘤的机制研究和抗肿瘤相关药物靶点的确认、药物筛选模型的建立及药物筛选、以及活性化合物的深入评价工作、利用生物信息学和网络药理学研发新药。

 

承担科研项目:

 

1.    2005 Thirty-Seventh Postdoctoral fund (NO.2005037103)

2.    2014 Award from Associates for Breast and Prostate Cancer Research

3.    2014 Award from Margie and Robert E.Peterson breast cancer program

4.    中国医学科学院药物所引进人才科研基金 110万)

5.    国家自然科学基金 (81573454) 60万)

6.    北京市自然科学基金717214220万)

7.    重大新药创制国家科技重大专项项目,2013ZX09402203、现代中药创新集群与数字制药技术平台、2013/01-2016/12 20万)

8.   中国医学科学院医学与健康科技创新工程 2050万)

9.    协和学者特聘教授研究基金 110万)

10.   活性与功能国家重点实验室研究基金 40万)

11.   十三五重大新药创制 139万)

12.   人工智能辅助药物发现与研究 90万)

 

论文发表,学术期刊编委及审稿人:

 

目前发表科研论文80余篇,其中在Journal of Clinical Investigation (JCI)Journal of the National Cancer Institute (JNCI) Journal of Clinical Oncology (JCO) PNAS Cancer research OncogeneHuman Molecular Genetics Journal of Investigative Dermatology OncotargetMolecular Cancer researchBreast Cancer Research Treatment Annual of surgical oncology Cell Biochemistry and Biophysics Clinical Hemorheology and Microcirculation世界著名期刊发表SCI论文60篇文章。

现为Acta Pharmaceutica Sinica B Oncotarget Pharmaceutical Biology Molecular medicine report Journal of Breast Cancer Cancer Investigation Asian Life ScienceOncology letter中国药理学通报,药学学报医药导报、中国药学杂志等杂志编委和审稿人。

   目前还担任中国药理学会全国代表,中国药理学会表观遗传药理专业委员,中国抗癌协和北京中西医整合肿瘤专业委员会常务委员。

 

发表论文:

 

1. Jinhua Wang*, Ying Qu*, Partha S. Ray et al. Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-κB signaling. Journal of Clinical Investigation. 2011;121(1):212-225. (The article was elected as highlighted article) (IF: 15.366)

2. Jinhua Wang, Wan Li, Ying Zhao et al. Members of FOX family could be drug targets of cancers. Pharmacol Ther. 2018 Jan;181:183-196. (IF: 11)

3. Xiangjin Zheng, Wan Li, Liwen Ren, Jinyi Liu Jinhua Wang*. The Sphingosine Kinase-1 / Sphingosine-1-Phosphate Axis in Cancer: Potential Target for Anticancer Therapy. Pharmacology & Therapeutics. 2019 Mar;195:85-99. (IF: 10.376).

4. P.S Ray, Jinhua Wang, Ying Qu, et al. Role of FOXC1 in regulation of   basal-like/triple-negative breast cancer. Journal of Clinical Oncology. 2009; 27: 562S (No 15S, Part I of II). (IF: 17.255)

5. Jensen TW, Ray T, Wang Jinhua, Li X et al. Diagnosis of Basal-Like Breast Cancer Using a FOXC1-Based Assay. J Natl Cancer Inst. 2015 Jun 3;107(8). (IF13.584)

6. Min Feng, Yi Bao, Zhimei Li, Jinhua Wang, Dave S.B. Hoon et al. RASAL2 activates RAC1 to promote triple-negative breast cancer progression. J Clin Invest. 2014; 124(12):5291-5304. (IF: 13.261)

7. Iida Y, Ciechanover A, Jinhua Wang, Dave Hoon et al. Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-κB Pathway in Melanoma. Clin Cancer Res. 2017 Aug 15; 23(16):4831-4842. (IF: 9.619)

8. Jinhua Wang*, Partha S. Ray*, Ying Qu* et al. FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer. Cancer Research. 2010; 70(10):1-7. (The pictures in the article were chosen as the cover of magazine) (IF: 8.576)

9. Jinhua Wang, I Kuiatse, AJ Casa, AV Lee, X Cui. JNK, essential for anticancer therapy-induced apoptosis promotes cancer breast progession. Cancer Research. 2009; 69( suppl.):(2).January 15,2009 (IF8.576)

10. Jinhua Wang, Sharon Hunag, Ling Takeshima et al. Acquire resistance to braf-inhibitor by increasing EGFR expression. Journal of Investigative Dermatology. 2015; 135:532-541. (IF: 7.216)

11. Jinhua Wang, Ying Qu, Xiaojiang Cui et al. FOXC1 regulates the functions of human basal-like breast cancer cells by activating NF-kB signaling. Oncogene, 2012 Nov 8;31(45):4798-802. (IF: 7.18)

12. Wan Li, Liwen Ren, Xiangjin Zheng, Jinyi Liu, Jinhua Wang*, Tengfei Ji*, Guanhua Du*. 3-O-Acetyl-11-keto-β-boswellic acid ameliorated aberrant metabolic landscape and inhibited autophagy in glioblastoma. Acta Pharmaceutica Sinica B, 2020, 10(2): 301-12. (IF:7.097)

13. Jinhua Wang, Wei hua, Sharon Huang et al. RASSF8 Regulates Progression of Cutaneous Melanoma through Nuclear Factor-κb. Oncotarget, 2015:6:30165-30177. (IF: 6.63)

14. Jinhua Wang, Hirose H, Du G et al. P-REX1 amplification promotes progression of cutaneous melanoma via the PAK1/P38/MMP-2 pathway. Cancer Lett. 2017 Oct 28;407:66-75. (IF: 6.491)

15. Jinhua Wang, Kelly K. Chong, Yoshitaka Nakamura et al. B7-H3 Associated with Tumor Progression and Epigenetic Regulatory Activity in Cutaneous Melanoma. Journal of Investigative Dermatology. 2013; 133(8):2050-8. (IF: 6.19)

16. ShuetTheng Lee, min feng, Jinhua Wang et al. Protein Tyrosine Phosphatase UBASH3B is Overexpressed in Triple-Negative Breast Cancer and Promotes Invasion and Metastasis. Proc Natl Acad Sci U S A. 2013, Jul 2; 110(27):11121-6. (IF: 9.598)

17. JianLi Chen, Han Zhang, XueQin Huang, HongYe Wan, Jie Li, XingXing Fan, Kathy Qian Luo, Jinhua Wang, XiaoMing Zhu1*, Jianfang Wang2*. Antiangiogenesis‑Combined Photothermal Therapy in the Second Near‑Infrared Window at Laser Powers Below the Skin Tolerance Threshold. Nano-Micro Lett. (2019) 11:93(IF: 9.043)

18. Marzese DM, Scolyer RA, Jinhua Wang, Kawas NP et al.. Epigenome-wide DNA Methylation Landscape of Melanoma Progression to Brain Metastasis Reveals Aberrations on Homeobox D Cluster Associated with Prognosis. Human Molecular Genetics, 2013; 23(1): 226-38. (IF: 7.541)

19. KatsuyaOhta, Hiromitsu Hoshino, Jinhua Wang et al. MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A. Oncotarget. 2015:6(5):3211-24. (IF: 6.63)

20. Jinyi LiuXiangjin ZhengXiaocong Pang, Cui Yang, Jinhua Wang*. GD3sa novel drug target of cancer.  Acta Pharmaceutica Sinica B. 2018 Sep;8(5):713-720.IF: 5.808  

21. Wan Li, Jinyi Liu, Weiqi Fu, Xiangjin Zheng, Liwen Ren, Shiwei Liu, Jinhua Wang*, Tengfei Ji*, Guanhua Du*. 3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase. Journal of Experimental & Clinical Cancer Research. 2018 Jul 3;37(1):132 (IF: 5.646 )     

22. Wan Li, Jie Yi, Xiangjin Zheng, Shiwei Liu, Weiqi Fu, Liwen Ren, Li Li, Dave S. B. Hoon, Jinhua Wang*, Guanhua Du. miR-29c plays a suppressive role in breast cancer by targeting the TIMP3/STAT1/FOXO1 pathway. Clinical Epigenetics. 2018 May 16;10:64.. (IF: 5.496 )                                 

23. Jie Yu, Jinhua Wang* et al. Overexpression of NSUN2 by DNA hypomethylation is associated with metastatic progression in human breast cancer. Oncotarget. 2017 Mar 28; 8(13):20751-20765. (IF: 5.168)

24. Jinhua Wang et al. Research progress on the Forkhead Box C1. Oncotarget, 2017 Nov 20;9(15):12471-12478.. (IF: 5.168)

25. Yi J, Gao R, Chen Y, Yang Z, Han P, Zhang H, Dou Y, Liu W, Wang W, Du G, Xu Y, Wang J*. Overexpression of NSUN2 by DNA hypomethylation is associated with metastatic progression in human breast cancer. Oncotarget. 2017 Mar 28;8(13):20751-20765. (IF: 5.168)

26. Wang Jinhua, Li Li, Liu Shiwei, Zhao Ying, Wang Lin, Du Guanhua. FOXC1 promotes melanoma by activating MST1R/PI3K/AKT pathway. Oncotarget. 2016 Dec 20; 7(51):84375-84387. (IF: 5.168)

27. Qin Tang, Liwen Ren, Jinyi Liu, Wan Li, Xiangjin Zheng, Jinhua Wang*, Guanhua Du*. Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4ATF3-CHOP axis. Cell Prolif. 2019 Oct 23:e12706. (IF: 5.039)

28. Jin-yi Liu, Wei-qi Fu, Xiang-jin Zheng, Wan Li, Li-wen Ren, Jin-hua Wang*, Cui Yang* and Guan-hua Du*. Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest. Acta Pharmacologica Sinica, 2020. (IF: 5.064)

29. Jinhua Wang, Isere Kuiatse, Adrian V. Lee et al. Sustained JNK Activity Promotes Epithelial-Mesenchymal Transition, Invasion, and Survival of Breast Cancer Cells by Regulating  ERK Activation. (Molecular Cancer Research, 2010; 8(2):266-277). (The article was elected as highlighted article) (IF: 4.937)

30. Jie Yi, Liwen Ren, Dandan Li, Jie Wu, Wan Li, Guanhua Du, Jinhua Wang*. Trefoil factor 1 (TFF1) is a potential prognostic biomarker with functional significance in breast cancers [J]. Biomedicine & Pharmacotherapy, 2020, 124(109827). (IF: 4.545)

31. Jinhua Wang*, Ying Qu*, Bingya Liu, Armando Giuliano et al. Elesclomol, counteracted by Akt survival signaling, enhances the apoptotic effect of chemotherapy drugs in breast cancer cells. (Breast Cancer Research and Treatment, 2010; 121(2):311-21. (IF: 4.467)

32. Jie Yi, Liwen Ren, Jie Wu, Wan Li, Xiangjin Zheng, Guanhua Du*, Jinhua Wang*.Apolipoprotein C1 (APOC1) as a novel diagnostic and prognostic biomarker for gastric cancer. Ann Transl Med. 2019 Aug;7(16):380.(IF: 3.689)

33. Liwen Ren, Xiangjin Zheng, Jinyi Liu, Wan Li, Weiqi Fu, Qin Tang, Jinhua Wang, Guanhua Dua∗∗Network pharmacology study of traditional Chinese medicines for stroke treatment and effective constituents screening. J Ethnopharmacol. 2019 Oct 5;242:112044.(IF: 3.414)

34. Jinhua Wang, WeiboKa, DaGong Sun et al. Synergistic effect of cytokines EPO, IL-3 and SCF on the proliferation, differentiation and apoptosis of erythroid progenitor cells. Clinical Hemorheology and microcirculation. 2007; 37(4):291-9. (IF: 3.398)

35. Jinhua Wang, WeiboKa, Zhiyu Tang et al. Rheological studies on precursor cells at different stage in mice. Clinical Hemorheology and microcirculation. 2003, 29:63-69. (IF: 3.398)

36. Jinhua Wang*, Xu Y, Li L et al. FOXC1 is associated with estrogen receptor alpha and affects sensitivity of tamoxifen treatment in breast cancer. Cancer Med. 2017 Jan; 6(1):275-287. (IF: 3.362)

37. Liwen Ren, Jie Yi, Wan Li, Xiangjin Zheng, Jinyi Liu, Jinhua Wang*, Guanhua Du*. Apolipoproteins and cancer. Cancer Med. 2019 Nov;8(16):7032-7043. (IF: 3.357)

38. Wan Li#, Xiangjin Zheng#, Liwen Ren, Weiqi Fu, Jinyi Liu, Jun Xv, Shiwei Liu, Jinhua Wang*, Guanhua Du*. Epigenetic hypomethylation and upregulation of GD3s in triple negative breast cancer [J]. Annals of Translational Medicine, 2019, 7(23): 723.(IF: 3.297)

39. Wen Sun, Jinhua Wang, Ciuping Chen et al. Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. Free Radic Biol Med. 2017 Jul; 108:433-444. (IF: 5.606)

40. Junke Song, Wen Zhang, Jinhua Wang, Haiguang Yang, Qimeng Zhou, Haigang Wang, Li Li, Guanhua Du*. Inhibition of FOXO3a/BIM signaling pathway contributes to the protective effect of  salvianolic acid A against cerebral ischemia/reperfusion injury. Acta Pharmaceutica Sinica B.2019,9:505-515. (IF: 5.808)

41. Xiaocong Pang, Weiqi Fu, Jinhua Wang, De Kang,Lvjie Xu,Ying Zhao, Ai-Lin Liu* and Guan-Hua Du*.Identification of Estrogen Receptor alpha Antagonists from Natural Products via In Vitro and In Silico Approaches. Oxidative Medicine and Cellular Longevity. (IF: 4.936) 

42. Xiaocong Pang, Ying Zhao, Jinhua Wang, Wan Li, Qian Xiang, Zhuo Zhang, Shiliang Wu, Ailin Liu*, Guanhua Du*, and Yimin Cui*. Competing Endogenous RNA and Coexpression Network Analysis for Identification of Potential Biomarkers and Therapeutics in association with Metastasis Risk and Progression of Prostate Cancer. Oxid Med Cell Longev. 2019 Aug 5;2019:8265958. (IF: 4.868)

43. Marzese DM, Liu M, Huynh JL, Wang J, Morton DL, Barkhoudarian G, Kelly DF, Hoon DS. Brain metastasis is predetermined in early stage of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome. Pigment Cell Melanoma Res. 2015 Jan; 28(1):82-93 (IF: 4.619)

44. Sanjay P. Bagaria*, Partha S. Ray*, Jinhua Wang, Alice Chung et al. Prognostic value of basal phenotype in HER2-overexpressing breast cancer. (Annual of surgical oncology, 2012; 19(3): 935-40. (IF: 4.308)

45. Partha S Ray*, Sanjay P Bagaria*, Jinhua Wang, Jaime M Shamonki. Basal-like breast cancer defined by FOXC1 expression offers superior prognostic value: a retrospective immunohistochemical study. (Annual of surgical oncology, 2011 18:3839–3847 (IF: 4.308)

46. Jingwen Zhang, Jinhua Wang, Diego M. Marzese, Xiaowen Wang, Zixiao Yang, Chunjie Li, Haibo Zhang, Jinsen Zhang, Clark C. Chen, Daniel F. Kelly, Wei Hua*, Dave S. B. Hoon*, Ying Mao*. B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma. Lab Invest. 2019 Jul;99(8):1117-1129. (IF: 3.684)

47. BinXiao, Jin-HuaWang, Cheng-YanZhou, Jun-MiaoChen, NaZhang, NaZhao, Xiao-YanHan, Yi-XuanNiu, Yu-BaoFeng, Guan-HuaDua. Ethno-medicinal study of Artemisia ordosica Krasch. (traditional Chinese/Mongolian medicine) extracts for the treatment of allergic rhinitis and nasosinusitis. J Ethnopharmacol. 2019.112262. Epub 2019 Oct 1. (IF: 3.414)

48. Dagong Sun, Jinhua Wang, Weijuan Yao et al. Tumorigenesis of murine erythroleukeiacell line transfected with exogenous p53 gene. Clinical Hemorheology and microcirculation. 2004, 30:117-126. (IF: 3.398)

49. Junke Song, Wen Zhang, Jinhua Wang, Haiguang, Guanhua Du*. Activation of Nrf2 signaling by salvianolic acid C attenuates NFκB mediated inflammatory response both in vivo and in vitro. International Immunopharmacology. 2018,63:299-310. (IF:3.118) 

50. Yang S, Wang J, Duanhua Du, et al. The natural product bergenin ameliorates lipopolysaccharide-induced acute lung injury by inhibiting NF-kappaB activition. J. Ethnopharmacol. 2017 Mar 22; 200:147-155. (IF: 2.981)

51. De Kang, Xiaocong Pang,Wenwen Lian, Lvjie Xu,Jinhua Wang, Hao Jia, Baoyue Zhang, Ai-Lin Liu*and Guan-Hua Du*.RSC Adv., 2018, 8, 5286. (IF: 2.936)

52. Jinhua Wang, WeiboKa, DaGongSun et al. Biochemical and biophysical studies on the precursor cells of mouse erythrocytes at different stages. Cell Biochemistry and Biophysics. 2006, 45:147-156. (The article was elected as highlighted article) (IF: 2.7)

53. Jin-Hua Wang*,Qing-Shan Liu*, Jian Cui, Zhi-Hong Yang et al. A novel acute anemia model for pharmacological research in mice by compelled acute exercise. Acta Pharmacologica Sinica. (2009) 30:1643-1647. (IF: 2.521)

54. Fangyun Sun* ,Xiuping Chen*, Jinhua Wang, et al. Arjunic acid, a strong free radical scavenger from Terminaliaarjuna. Am J Chin Med. 2008; 36(1):197-207291-9 (IF: 1.969)

55. Jinhua Wang, WeiboKa, Dagong Sun et al Biophysical and biorheology studies on the precursor cells at different stages. Science in China (Series. C). 2002, 45: 421-428. (IF: 1.2)

56. Yepeng Luan*, Jinyi Liu, Jianjun Gao, Jinhua Wang*. The Design and Synthesis of Novel Phenothiazine Derivatives as Potential Cytotoxic Agents [J]. Letters in Drug Design & Discovery, 2020, 17:57-67. (IF: 1.169)

57. Lin Wang, Jinhua Wang, Guanhua Du et al. Actinomycin D synergistically enhances the cytotoxicity of CDDP on KB cells by activating P53 via decreasing P53-MDM2 complex. J Asian Nat Prod Res. 2017 Jun; 19(6):630-643. (IF: 1.071)

58. Wei CJ, Jinhua Wang, Guanhua Du et al. Synthesis and antitumor activities of sinomenine derivatives on rings A and C. J Asian Nat Prod Res. 2017 Nov 1:1-15. (IF: 1.071)

59. Chen X, Sun F, Ma L, Jinhua Wang, Qin H, Guanhua Du. In vitro evaluation on the antioxidant capacity of triethylchebulate, an aglycone from Terminaliachebula Retz fruit. Indian Pharmacol. 2011 May; 43(3):320-3. 291-9 (IF: 0.667)

60. 任利文,郑湘锦,李婉,王金华,杜冠华. 中药雷公藤毒性的历史认识与评价。医药导报刊印中

61. 伍友春,张昆,康志龙,赵新,王金华,许焕丽. 白花蛇舌草醇提物和半枝莲醇提物联用抗胰腺癌作用及机制研究 [J]. 药物评价研究, 2020, 43(7): 1233-8.

62.刘金宜,任利文,李莎,唐琴,李婉,郑湘锦,王金华,杜冠华.肿瘤免疫和代谢药物靶点研究进展[J].药学学报,2019,54(10):1718-1727.

63.富炜琦,王金华,李婉,王霖,杜冠华.中药苦木毒的历史认识与现代研究[J].中药药理与临床,2019,35(02):154-156.

64.郑湘锦,任利文,李婉,王金华,杜冠华.青风藤安全性研究进展[J].医药导报,2019,38(11):1430-1433.

65.刘金宜,富炜琦,杜冠华,王金华,杨淬.ST8Sia1基因过表达载体构建与鉴定及对人黑色素瘤细胞增殖的影响[J].中国药理学通报,2019,35(05):733-739.78.

66.王金华,李莉,杜冠华.中药天仙子的历史认识与评价[J].中药药理与临床,2018,34(05):163-165.

67. 于子茹,李莉,王金华,王振中,萧伟,杜冠华桂枝茯苓胶囊原料药及其组分对人源乳腺癌细胞株增殖的影响中国中西医结合杂志2018年2月第38卷第2期

68. 周启蒙王金华杜冠华两种晶型尼莫地平片剂在恒河猴体内药代动力学研究. 药学学报,201752(12)1918-1923.

69. 刘师伟,王金华,杨静Vaspin 和肥胖及 2 型糖尿病.中华内分泌代谢杂志2011(27).No.5.

70. 王金华蒋玉辉唐志宇曾柱生长发育过程中血细胞流变学特性的研究进展( 综述 ).中国生物医学工程学报2006(25).No.2.

71. 王金华韩光亮张天泰杜冠华基于FP法的EPOR 配体高通量筛选模型.中国药理学通报2006 Jan221):114~7.

72. 王金华孙芳云杜冠华诃子的药理作用研究进展.中国民族医药杂志1006-6810(2006)06-0045-03

73. 王金华杜冠华促红细胞生成素的信号传导及其生物学作用的研究进展.医学分子生物学杂质200526):440-443.

74. 王金华,喀蔚波,孙大公等.用激光衍射法测量网织红细胞膜剪切弹性膜量(E)及表面粘度(μm).中国生物医学工程学报 20052404 468-471.

75. 王金华,喀蔚波,孙大公等.不同发育阶段红系造血细胞的流变特性的研究.中国生物医学工程学报 2004(23).No.1.

76. 王金华,喀蔚波,唐志宇等.小鼠网织红细胞微观流变学特性的研究.生物物理学报2004年第3 173-177.

77. 王金华,岳黎,唐军民等.CFU及其分化细胞的生物物理特性.生物物理学报 200319367-371.

78. 王金华,姚伟娟,喀蔚波.红细胞和内皮细胞的粘附研究进展.北京生物医学工程 200120302-305.

79. 王金华,喀蔚波孙大公文宗曜.病理条件下白细胞与内皮细胞的粘附.中国血液流变学杂质200010(4).

80. 孙芳云,王金华,张斌,梁智,秦海林,杜冠华.大花红景天的抗氧化性溶血作用研究.中药药理与临床20062234.

81. 岳黎敏,唐军民,苏安英,唐岩,王金华,汪涛,文宗曜.新型CKLF1对家兔红系造血祖细胞增殖分化的影响解剖学报20043504-382.

国际专利:

Patent 1: METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT OF PRIMARY AND METASTATIC BASAL-LIKE BREAST CANCER AND OTHER CANCER TYPES  Patent No. US 9074253 B2  授权日: 2015.7.7.

Patent 2: DIAGNOSIS OF PRIMARY AND METASTATIC BASAL-LIKE BREAST CANCER AND OTHER CANCER TYPES  Patent No. EP 2486149 B1  授权日: 2015.6.17.

国内专利:

专利1醉茄素A在制备预防或治疗胶质母细胞瘤药物中的应用王金华等。申请号:201810266304.0

专利2乳香酸及其衍生物的制备与其抗神经胶质瘤的用途。王金华等。申请号:201810581480.3

专利 3:阿伐麦布在制备预防或治疗胶质母细胞瘤药物中的应用 王金华等。申请号:201811248470.4

专利 4载脂蛋白C 1在作为胃癌诊断及预后评价生物标记物中的应用。王金华等。申请号:201910163695.8

专利 5青藤碱类化合物在制备预防或治疗神经胶质瘤药物中的应用王金华等。申请号:201910671599.4

专利 6:三个唑类化合物在制备抗神经胶质瘤药物中的应用。王金华等。申请号:202010189295.7

专利 7:黄芩素在制备预防和/或治疗新冠病毒感染疾病的药物中的应用。杜冠华,吕扬….王金华等。申请号:202010133944.1

参编专著:

1.  丹参大全.  ISBN:978-7-117-09935-6/R.9936.  2008, Page: 242-248

2.  人类疾病动物模型. ISBN: 978-7-81116-231-8.   2007, Page: 88-85

3. 《天然小分子药物-源自于植物的小分子药》副主编 2018

4. 《中药材之古今研究概评》2018

5.  Nature small molecule drugs from plants 2018

6.  中国医学科技发展报告2019

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