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ZHANG JINLAN

Time:2013/12/10 Source: Read:4611


ZHANG JINLAN

Name: ZHANG JINLAN

Date of Birth: 25th Feb, 1969

Position: Professor

Organization: Institute of Materia Medica, Chinese Academy of Medical Sciences, 2 NanweiI Road, Xuanwu District, Beijing, 100050

Work Phone: 010-83154880

Mobile Phone: 13552485658

E-mail: zhjl@imm.ac.cn

Educational Background

l  PhD candidate in pharmaceutical analysis,  09/1999-07/2002Institute of Materia Medica, Chinese Academy of  Medical Sciences, Peking Union Medical College( PUMC)

l  MS in pharmaceutical analysis, 09/1992-07/1995Department of Pharmaceutical Analysis, Institute of Materia Medica, Chinese Academy of Medical Science, PUMC

l  BS in Pharmacy, 09/1987-07/1992College of Pharmacy, Beijing University

Degree and Major: PH.D, Pharmaceutical Analysis

Research Experience:

l  Metabolism of new drugs and nature products by hybrade tandem mass spectrometry techniques

l  Develop new analytical techniques to characterize and identify active components of TCM.

l  Develop new analytical techniques to detect drug in biological samples Develop new analytical method for lipidomics and biomarkers related to desease

l  Pharmacokinetic study of new drugs and leader compounds

Work Experience:

l  09/2000-07/2002Associated professorDepartment of Pharmaceutical Analysis, Institute of Materia Medica, Chinese Academy of  Medical Sciences, Peking Union Medical College( PUMC)

l  08/2002-05/2004Post Doctor, College of Pharmacy, Beijing University

l  06/2004 to now Associated professor and professorDepartment of Pharmaceutical Analysis, Institute of Materia Medica, Chinese Academy of  Medical Sciences, Peking Union Medical College( PUMC)

Resent Publications:

1 Ying Jin, Cai-Sheng Wu, Jin-Lan Zhang, Ying-Fei LiA new strategy for the discovery of epimedium metabolites using high-performance liquid chromatography with high resolution mass spectrometryAnalytica Chimica Acta, 768 (2013) :111– 117

2 Qiang Ren, Caisheng Wu, Jinlan Zhang,Use of on-line stop-flow heart-cutting two-dimensional high performance liquid chromatography for simultaneous determination of 12 major constituents in tartary buckwheat (Fagopyrum tataricum Gaertn) , Journal of Chromatography A, 1304 (2013) :257– 262

3 Feng Qu, Cai-Sheng Wu, Jin-Feng Hou, Ying Jin, Jin-Lan ZhangSphingolipids as New Biomarkers for Assessment of Delayed-Type Hypersensitivity and Response to TriptolidePLOS one, 72012):1-12

4 Qiang Ren, Caisheng Wu, Yan Ren, Jinlan ZhangCharacterization and identification of the chemical constituents from tartary buckwheat (Fagopyrum tataricum Gaertn) by high performance liquid chromatography/photodiode array detector/linear ion trap FTICR hybrid mass spectrometryFood Chemistry, 136 (2013) :1377–1389

5 Jinfeng Hou, Feng Qu, Caisheng Wu, Qiang Ren, Jinlan Zhang,Quantitative determination and pharmacokinetic study of the novel anti-Parkinson’s disease candidate drug FLZ in rat brain by high performance liquid chromatography–tandem mass spectrometryJournal of Pharmaceutical and Biomedical Analysis, 66 (2012): 232– 239.

6 Yan Ren Caisheng WuJinlan ZhangSimultaneous screening and determination of 18 illegal adulterants in herbal medicines and health foods for male sexual potency by ultra-fast liquid chromatographyelectrospray ionization tandem mass spectrometryJ. Sep. Sci., 352012: 2847–2857

7 Yilin Wang, Chunguang Ding, Caisheng Wu, Kehe Du, Jinlan Zhang, Hailin Qin, Jinfeng Hou, Guanhua DuHPLC–MS and HPLC–MS/MS analysis of seven active constituents of Xiao-Xu-Ming decoction and application to a pharmacokinetic study after oral administration to rat Acta Pharmaceutica Sinica B , 2(2) (2012):186–195

8 Wu CS, Zhang JL, Zhou TH, Guo BL, Wang YL, Hou JF. Simutaneous determination of seven flavonoids in dog plasma by ultra-performance liquid chromatography-tandem mass spectrometry and its application to a bioequivalence study of bioactive components in Herba Epimedii and Er-Xian Decoction[J]. Journal of Pharmaceutical and Biomedical Analysis, 54(2011): 186-191.

9 Chun-Yan Niu, and Jin-Lan Zhang,Quantitative analysis and chromatographic fingerprinting of the semen zizyphi spinosaeby ultra-high-performance liquid chromatography coupled with diode-array detectorJournal  separation science, 34(2011):2989-2996

10 Chun-Yan Niu, Cai-Sheng Wu, Yu-Xin Sheng and Jin-Lan Zhang, Identification and characterization of flavonoids from semen zizyphi spinosae by high-performance liquid chromatography/linear ion trap FTICR hybrid mass spectrometryJournal of Asian Natural Products Research 12(4)(2010):300–312.

11. Yilin Wang, Chunguang Ding, Kehe Du, Yao Xiao, Caisheng Wu, Jinlan Zhang,Hailin Qin and Guanhua DuIdentification of active compounds and their metabolites by high-performance liquid chromatography/electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry from Xiao-xu-ming decoction (XXMD)Rapid Commun. Mass Sp, 23 (2009): 2724–2732..

12. Qiao, YL; Zhang, YH; Zhang, W; Zhang, JL. 2009. A Rapid Resolution Liquid Chromatographic Method for Fingerprint Analysis of Raw and Processed Caowu (Aconitum kusnezoffii),J. of AOAC International 92 (2) ( 2009): 653-662.

13. Qiao, YL; Sheng, YX; Wang, LQ; Zhang, JL., Development of a Rapid Resolution Liquid Chromatographic Method for Simultaneous Analysis of Four Alkaloids in Rhizoma coptidis Under Different Cultivation Conditions. J. of AOAC Internationa, 92 (2)(2009): 663-671.

14. Kehe Du, Caisheng Wu, Chunguang Ding, Shanlin Zhao, Hailin Qin and Jinlan Zhang, Simultaneous LC–MS Analysis and of Wogonin and Oroxylin A in Rat Plasma, and Pharmacokinetic Studies After Administration of the Active Fraction from Xiao-Xu-Ming Decoction. Chromatographia, 69(11-12 ) (2009):1259-1266.

15. Caisheng Wu, Yuxin Sheng, Yinghao Zhang, Jinlan Zhang and Baolin GuoIdentification and characterization of active compounds and their metabolites by high-performance liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometry after oral administration of a herbal extract of Epimedium koreanum Nakai to ratsRapid Commun. Mass Sp, 22 (2008): 2813–2824.

16. W. Zhang, Y.X. Sheng, J.L. Zhang, Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by high-performance liquid chromatography–electrospray ionization mass spectrometric method. Phytomedicine, 15 (10) (2008): 844-850.

17. Yao Xiao, Ying-hao Zhang, Yu-xin Sheng, Jin-lan Zhang. LC-MS determination and pharmacokinetic studies of paeonol in rat plasma after administration of different compatibility of Su-Xiao-Xin-Tong prescriptions. Biomed Chromatogr, 22 (5) (2008): 527-534.

18. Li-bo Li, Jin-lan Zhang, Yu-xiang Wang, Huai-ling Wei, Geng-tao Liu. Establishment of a HPLC method for preclinical pharmacokinetic study of the novel anti-Parkinson's disease candidate drug FLZ in rats. Biomed Chromatogr, 22 (8)( 2008): 867-872.

19. Chunguang Ding, Yuxin Sheng, Yinghao Zhang, Jinlan Zhang, Guanhua Du. Identification and comparison of metabolites after oral administration of essential oil of Ligusticum Chuanxiong or its major constituent Ligustilide in rats. Planta Med, 74 (2008):1684-1692.

20. Yi Li, Zhaoyang Zhang and Jinlan Zhang, Determination of hydroxysafflor yellow A in rat plasma and tissues by HPLC after oral administration of safflower extract; Biomedical Chromatography, 21(2007)326-334.

 

 

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