1. 天然产物对神经和免疫的调控机制
2. 生物熵算法在药物研发中的应用

1. Gao T-L, Guo H-H, Jiang J-D. Neg-Entropy Mechanism as a Target for Natural Medicines. Engineering 2024,38(7):11-12.
2. Shen Z#, Guo Y-D#, Tang M-Z#, Zhou P#, Su Y-X, Shen H-R, Li T, Jiang W, Han Y-X, Tie C*, Cui J-J*, Gao T-L*, Jiang J-D. Dexborneol Amplifies Pregabalin’s Analgesic Effect in Mouse Models of Peripheral Nerve Injury and Incisional Pain. Antioxidants 2024;13(7):803.
3. Qi H#, Sun Z#, Gao T#. et al. Genetic fusion of CCL11 to antigens enhances antigenicity in nucleic acid vaccines and eradicates tumor mass through optimizing T-cell response. Mol Cancer 2024; 23:46.
4. Guo H#, Han Y#, Rong X#, Shen Z#, Shen H, Kong L, Guo Y, Li J, Xu B, Gao T*, Wang L*, Tie C*, Jian-Dong Jiang. Alleviation of allergic asthma by rosmarinic acid via gut-lung axis. Phytomedicine 2024; 126: 155470.
5. Shen H, Wang Z, Shen Z, Liu T, Guo Y, Gao T, Guo H*, Han Y*, Jiang J-D. Bacterial butyrate mediates the anti-atherosclerotic effect of silybin. Biomed Pharmacother. 2023; 169:115916.
6. Han CJ#, Shen Z#, Li T#, Tang M#, Jiang W, Tie C, Guo H*, Gao J*, Han Y*, Gao T*. The common neurological basis and targeted therapeutic approaches for chronic pain and opioid addiction. Neuro Endocrinol Lett. 2023; 44(3):175-190.
7. Han CJ#, Shen Z#, Tang M#, Jiang W, Gao T*. Antinociceptive effects of cefadroxil and ceftriaxone in experimental animal models of pain. Neuro Endocrinol Lett. 2023; 44(5):309-320.
8. Guo H#, Shen H#, Wang L, Luo Z, Zhang J, Zhang H, Gao T*, Han Y*, Jiang J-D*. Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases. Biomed Pharmacother. 2023; 163:114754.
9. Kong L#, Rong X#*, Yan P, Qin T, Zhang X, Kang Y, Cheng B, Su W, Gao T, Tie C*. The influence of Hyssopus cuspidatus Boriss extract on lipid mediators metabolism network in asthmatic mice. Front. Pharmacol. 2023; 14:1066643. doi: 10.3389/fphar.2023.1066643.
10. Guo H#, Shen H#, Tang M, Sheng N, Ding X, Lin Y, Zhang J, Jiang J-D, Gao T*, Wang L*, Han Y*. Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis. J Ethnopharmacol. 2023; 306:116158. doi: 10.1016/j.jep.2023.116158.
11. Jiang W#, Tang M#, Yang L#, Zhao X#, Gao J#, Jiao Y, Li T, Tie C, Gao T*, Han Y*, Jiang JD*. Analgesic Alkaloids Derived from Traditional Chinese Medicine in Pain Management. Front Pharmacol. 2022;13:851508. doi: 10.3389/fphar.2022.851508.
12. Wang Y, Tong Q, Ma SR, Zhao ZX, Pan LB, Cong L, Han P, Peng R, Yu H, Lin Y, Gao T, Shou JW, Li XY, Zhang XF, Zhang ZW, Fu J, Wen BY, Yu JB, Cao X, Jiang JD. Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson's disease by regulating gut microbiota. Signal Transduct Target Ther. 2021; 6(1):77.
13. Gao T#, Li T#, Jiang W#, Fan W#, Xu X-J, Zhao X, Yin Z, Guo H, Wang L, Gao J*, Han Y*, Jiang J-D* and Wang D*. Antinociceptive Effects of Sinomenine Combined with Ligustrazine or Paracetamol in Animal Models of Incisional and Inflammatory Pain. Front. Physiol. 2021; 11:523769.
14. Dondalska A, Rönnberg E, Ma H, Pålsson SA, Magnusdottir E, Gao T, Adam L, Lerner EA, Nilsson G, Lagerström M, Spetz AL. Amelioration of Compound 48/80-Mediated Itch and LL-37-Induced Inflammation by a Single-Stranded Oligonucleotide. Front Immunol. 2020; 11:559589.
15. Jiang W#, Fan W#, Gao T#, Li T#, Yin Z, Guo H, Wang L, Han Y*, Jiang J-D. Analgesic Mechanism of Sinomenine against Chronic Pain. Pain Research and Management 2020; 2020:1876862.
16. Ma H#, Gao T#, Jakobsson JET, Weman HM, Xu B, Larhammar D, Lagerström MC*.The Neuropeptide Y Y2 Receptor Is Coexpressed with Nppb in Primary Afferent Neurons and Y2 Activation Reduces Histaminergic and IL-31-Induced Itch. J Pharmacol Exp Ther. 2020; 372(1):73-82.
17. Gao T*, Jiao Y, Liu Y, Li T, Wang Z, Wang D*. Protective Effects of Konjac and Inulin Extracts on Type 1 and Type 2 Diabetes. J Diabetes Res. 2019; 2019:3872182.
18. Gao T*, Li T, Jiang W, Fan W, Jiang JD. Exploratory study data for determining the adverse effects of sinomenine plus gabapentin or ligustrazine hydrochloride and the pharmacokinetic insights of sinomenine in plasma and CNS tissue. Data Brief. 2019; 27:104633.
19. Gao T#, Shi T#, Wiesenfeld-Hallin Z, Li T, Jiang JD*, Xu XJ. Sinomenine facilitates the efficacy of gabapentin or ligustrazine hydrochloride in animal models of neuropathic pain. Eur J Pharmacol. 2019; 854:101-108.
20. Fernandez-Zafra T, Gao T, Jurczak A，Sandor K, Hore Z, Agalave NM, Su J, Estelius J, Lampa J, Hokfelt T, Wisenfeld-Hallin Z, Xu X, Denk F，Svensson CI*. Exploring the transcriptome of resident spinal microglia after collagen antibody-induced arthritis. Pain 2019; 160(1): 224-36.
21. Gao T#，Ma H#, Xu B, Bergman J, Larhammar D, Lagerstrom MC*. The Neuropeptide Y System Regulates Both Mechanical and Histaminergic Itch. Journal of Investigative Dermatology 2018; 138:2405-11.
22. Gao T*, Lagerstrom MC. The anti-inflammatory alkaloid aloperine in Chinese herbal medicine is potentially useful for management of pain and itch. Scand J Pain 2015; 8:25-26.
23. Gao T*, Shi T, Wiesenfeld-Hallin Z, Svensson CI, Xu XJ. Sinomenine alleviates mechanical hypersensitivity in mice with experimentally-induced rheumatoid arthritis. Scand J Pain 2015; 7:9-14. DOI:10.1016/j.sjpain.2014.12.003.
24. Su J, Gao T, Shi TJ, Xiang Q, Xu XJ, Wiesenfeld-Hallin Z, Hökfelt T, Svensson CI*. Phenotypic changes in dorsal root ganglion and spinal cord in the collagen antibody-induced arthritis mouse model. J Comp Neurol. 2015; 523(10):1505-28.
25. Gao T*, Shi T, Wang DQ, Wiesenfeld-Hallin Z, Xu XJ. Repeated sinomenine administration alleviates chronic neuropathic pain-like behaviors in rodents without producing tolerance. Scand J Pain 2014; 5(4):249-55.
26. Carlsson-Jonsson A*, Gao T, Hao JX, Fransson R, Sandström A, Nyberg F, Zsuzsanna Wiesenfeld-Hallin Z, Xu XJ*. N-terminal truncations of substance P1-7 amide affect its action on spinal cord injury-induced mechanical allodynia in rats. Eur J Pharmacol 2014; 738:319-25.
27. Gao T*（通讯作者）, Hao JX, Wiesenfeld-Hallin Z, Xu XJ. Quantitative test of responses to thermal stimulation in spinally injured rats using a Peltier thermode: a new approach to study cold allodynia. J Neurosci Methods 2013; 212:317– 321.
28. Gao T, Hao JX, Wiesenfeld-Hallin Z, Xu XJ*. Activation of TRPM8 cold receptor triggers allodynia-like behavior in spinally injured rats. Scand J Pain 2013; 4:33–37.
29. Gao T, Hao JX, Wiesenfeld-Hallin Z, Wang DQ, Xu XJ*. Analgesic effect of sinomenine in rodents after inflammation and nerve injury. Eur J Pharmacol 2013; 721:5-11.
30. Li L, Wang B, Gao T, Zhang X, Hao JX, Vlodavsky I, Wiesenfeld-Hallin Z, Xu XJ, Li JP*. Heparanase overexpression reduces carrageenan-induced mechanical and cold hypersensitivity in mice. Neurosci Lett 2012; 511(1):4-7.
31. Dominguez CA, Ström M, Gao T, Zhang L, Olsson T, Wiesenfeld-Hallin Z, Xu XJ, Piehl F*. Genetic and sex influence on neuropathic pain-like behaviour after spinal cord injury in the rat. Eur J Pain 2012; 16(10):1368-77.