1. Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis. Jiawang Liu#, Jia-Yan Lu#, Chen Zhang#, Qingyang Zhou#, Cooper S. Jamieson, Changhui Shang, K. N. Houk*, Jiahai Zhou*, and Youcai Hu*. Nature Chemistry, 2023, 15(8), 1083-1090.
2. Flavin-Dependent Monooxygenase-Mediated 1,2-Oxazine Construction via Meisenheimer Rearrangement in the Biosynthesis of Paeciloxazine. Daojiang Yan#, Kunya Wang#, Songlin Bai#, Bingyu Liu#, Jian Bai, Xiangbing Qi, and Youcai Hu*. Journal of the American Chemical Society, 2022, 144(9), 4269-4276.
3. Biosynthesis of rumbrins and inspiration for discovery of HIV inhibitors. Beifen Zhong#, Jun Wan#, Changhui Shang#, Jiajia Wen, Yujia Wang, Jian Bai, Shan Cen*, Youcai Hu*. Acta Pharmaceutica Sinica B, 2022, 12(11): 4193-4203.
4. Enzymatic Dimerization in the Biosynthetic Pathway of Microbial Natural Products. Jiawang Liu#, Anan Liu# and Youcai Hu*. Natural Product Reports, 2021, 38(8), 1469-1505.
5. Self-Resistance in the Biosynthesis of Fungal Macrolides Involving Cycles of Extracellular Oxidative Activation and Intracellular Reductive Inactivation. Yalong Zhang, Jian Bai, Le Zhang, Chen Zhang, Bingyu Liu, and Youcai Hu*. Angewandte Chemie International Edition, 2021, 60(12), 6639–6645.
6. Genome mining combined metabolic shunting and OSMAC strategy of an endophytic fungus leads to the production of diverse natural products. Qian Wei#, Jian Bai#, Daojiang Yan, Xiuqi Bao, Wenting Li, Bingyu Liu, Dan Zhang, Xiangbing Qi, Dequan Yu, Youcai Hu*. Acta Pharmaceutica Sinica B, 2021, 11(2), 572-587.
7. Enzymatic Intermolecular Hetero-Diels–Alder Reaction in the Biosynthesis of Tropolonic Sesquiterpenes.Qibin Chen#, Jie Gao#, Cooper Jamieson, Jiawang Liu, Masao Ohashi, Jian Bai, Daojiang Yan, Bingyu Liu, Yongsheng Che, Yanan Wang, K. N. Houk*, and Youcai Hu*. Journal of the American Chemical Society, 2019, 141(36), 14052-14056.
8. Biosynthesis of Heptacyclic Duclauxins Requires Extensive Redox Modifications of the Phenalenone Aromatic Polyketide. Shu-Shan Gao#, Tao Zhang#, Marc Garcia-Borras, Yiu-Sun Hung, John M. Billingsley, K. N. Houk*, Youcai Hu* and Yi Tang*. Journal of the American Chemical Society, 2018, 140(22), 6991−6997.
9. Epigenetic modification in histone deacetylase deletion strain of Calcarisporium arbuscula leads to diverse diterpenoids.Jian Bai, Rong Mu, Man Dou, Daojiang Yan, Bingyu Liu, Qian Wei, Jun Wan, Yi Tang, Youcai Hu*. Acta Pharmaceutica Sinica B, 2018, 8(4), 687–697.
10. A Cascade of Redox Reactions Generates Complexity in the Biosynthesis of the Protein Phosphatase-2 Inhibitor Rubratoxin A. Jian Bai#, Daojiang Yan#, Tao Zhang, Yongzhi Guo, Yunbao Liu, Yi Zou, Mancheng Tang, Bingyu Liu, Qiong Wu, Shishan Yu*, Yi Tang*, and Youcai Hu*. Angewandte Chemie International Edition, 2017, 56(17), 4782-4786.