Nanomedicine-based combination anticancer therapy between nucleic acids and small-molecular drugs. Wei Huang#, Liqing Chen#, Lin Kang#, Mingji Jin, Ping Sun, Xin Xin, Zhonggao Gao*, You Han Bae. Advanced Drug Delivery Reviews, 2017, 115:82-97.
Effective Oral Delivery of Exenatide-Zn2+ complex through Distal Ileum-Targeted Double Layers Nanocarriers Modified with Deoxycholic Acid and Glycocholic Acid in Diabetes Therapy. YingHan, WeiLiu, Liqing Chen, Xin Xin, Qiming Wang, Xintong Zhang, Mingji Jin, Zhonggao Gao*, Wei Huang*. Biomaterials, 2021: 120944.
Systemic siRNA delivery with a dual pH-responsive and tumor-targeted nanovector for inhibiting tumor growth and spontaneous metastasis in orthotopic murine model of breast carcinoma. Bo Fan, Lin Kang, Liqing Chen, Ping Sun, Mingji Jin, Qiming Wang, You Han Bae, Wei Huang*, Zhonggao Gao*. Theranostics, 2017, 7(2):357-376.
Anti-tumor effects in mice induced by survivin-targeted siRNA delivered through polysaccharide nanoparticles.Feifei Yang#, Wei Huang# , Yunfei Li, Shan Liu, Mingji Jin, Yuli Wang, Lihua Jia, Zhonggao Gao*. Biomaterials, 2013, 34(22):5689-5699.
Recent advances in drug delivery systems for targeting cancer stem cells. Hongxia Duan, Yanhong Liu, Zhonggao Gao, Wei Huang*. Acta Pharmaceutica Sinica B, https://doi.org/10.1016/j.apsb.2020.09.016.
Enhancing anti-melanoma outcomes in mice using novel chitooligosaccharide nanoparticles loaded with therapeutic survivin-targeted siRNA. Xuan Liu, Liqing Chen,YingyingZhang, XinXin, LinglingQi, MingjiJin, Youyan Guan*, ZhonggaoGao*, WeiHuang*. 2021, European Journal of Pharmaceutical Sciences, https://doi.org/10.1016/j.ejps.2020.105641.
Improving anti-tumor outcomes for palliative intratumoral injection therapy through lecithin-chitosan nanoparticles loading paclitaxel-cholesterol complex. Xiao-yang Chu#, Wei Huang#, Yu-li Wang, Ling-wei Meng, Li-qing Chen, Ming-ji Jin, Lu Chen, Chun-hong Gao, Cheng Ge, Zhong-gao Gao*, Chun-sheng Gao*. International Journal of Nanomedicine, 2019, 14:689-705.
Improving glioblastoma therapeutic outcomes via doxorubicin-loaded nanomicelles modified with borneol. Lingwei Meng, Xiaoyang Chu, Haoyue Xing, Xuan Liu, Xin Xin, Liqing Chen, Mingji Jin,Youyan Guan*, Wei Huang*, Zhonggao Gao*.2019, International Journal of Pharmaceutics, 567: 118485.
Improving anti-tumor outcomes for colorectal cancer therapy through in situ thermosensitive gel loading harmine. Zhenzhen Li, Liqing Chen, Chenghui He, Ying Han, Mingfeng Han, Yingying Zhang, Lingling Qi, Wei Huang*, Zhonggao Gao*, Xuezhong Xing*, Jianguo Xing*. American Journal of Translational Research, 2020;12(5):1658-1671.
Smart polymeric nanoparticles with pH-responsive and PEG-detachable properties for co-delivering paclitaxel and survivin siRNA to enhance antitumor outcomes. Mingji Jin, Guangming Jin, Lin Kang, Liqing Chen, Zhonggao Gao*, Wei Huang*. International Journal of Nanomedicine, 2018, 13:2405-2426.
siRNA-loaded poly(histidine-arginine)6-modifed chitosan nanoparticle with enhanced cell-penetrating and endosomal escape capacities for suppressing breast tumor metastasis.Ping Sun, Wei Huang*, Lin Kang, Mingji Jin, Bo Fan, Hongyan Jin, Qiming Wang, Zhonggao gao*. International Journal of Nanomedicine, 2017, 12:3221-3234.
Lx2-32c-loaded polymeric micelles with small size for intravenous drug delivery and their inhibitory effect on tumor growth and metastasis in clinically associated 4T1 murine breast cancer.Liqing Chen, Wei Huang*, Zhonggao Gao*, Weishuo Fang, Mingji Jin. International Journal of Nanomedicine, 2016, 11:5457-5472.
Inhibition of murine breast cancer growth and metastasis by survivin-targeted siRNA using disulfide cross-linked linear PEI. Shan Liu#, Wei Huang#, Mingji Jin, Bo Fan, Guimin Xia, Zhonggao Gao*. European Journal of Pharmaceutical Sciences, 2016, 82:171-182.
Optimization of the process variables of tilianin-loaded composite phospholipid liposomes based on response surface-central composite design and pharmacokinetic study.Cheng Zeng, Wen Jiang, Meie Tan, Xiaoyi Yang, Chenghui He, Wei Huang*, Jianguo Xing*. European Journal of Pharmaceutical Sciences, 2016, 85:123-131.
Inhibiting the proliferation, migration and invasion of triple negative breast cancer cells through anti-tumor human serum albumin nanoparticles loading aziditaxel as a novel taxane derivative.Li-qing Chen#, Zhe-ming Zhang#, Wei Huang*, Zhong-gao Gao*, Wei-shuo Fang, Ming-ji Jin, Lian Yu. Pharmazie, 2017, 72(3):152-160.
Development of solid lipid nanoparticles containing total flavonoid extract from Dracocephalum moldavica L. and their therapeutic effect against myocardial ischemia-reperfusion injury in rats.Mei-e Tan, Cheng-hui He, Wen Jiang, Cheng Zeng, Ning Yu, Wei Huang*, Zhong-gao Gao, Jian-guo Xing*. International Journal of Nanomedicine, 2017, 12:3253-3265.
Enhancing in vivo bioavailability in beagle bogs of GLM-7 as a novel anti-leukemia drug through a self-emulsifying drug delivery system for oral delivery.Yuli Wang#, Ning Yu#, Rui Guo#, Meiyan Yang, Li Shan, Wei Huang*,Wei Gong, Shuai Shao, Xiaoping Chen, Chunsheng Gao*. Current Drug Delivery, 2016, 13:131-142.
Novel ethylcellulose-coated pellets for controlled release of metoprolol succinate without lag phase: characterization, optimization and in vivo evaluation. Yuli Wang, Jiahui Yang, Yong Qian, Meiyan Yang, Yan Qiu, Wei Huang*, Li Shan, Chunsheng Gao*. Drug Development and Industrial Pharmacy, 2015, 41(7):1120-1129.
Simultaneous Determination of Six Active Compounds in Yixin Badiranjibuya Granules, a Traditional Chinese Medicine, by RP-HPLC-UV Method.Ning Yu, ChenHui He, Gulistan Awuti, Cheng Zeng, JianGuo Xing*, Wei Huang*. Journal of Analytical Methods in Chemistry, 2015:974039.
The influence of the gut microbiota on the bioavailability of oral drugs.Xintong Zhang, Ying Han, Wei Huang, Mingji Jin, Zhonggao Gao. Acta Pharmaceutica Sinica B, In press, https://doi.org/10.1016/j.apsb.2020.09.013
Improved Antitumor Outcomes for Colon Cancer Using Nanomicelles Loaded with the Novel Antitumor Agent LA67.Minhu Cui, Mingji Jin, Mingfeng Han, Yingda Zang, Chuangjun Li, Dongming Zhang, Wei Huang, Zhonggao Gao*, Xuezhe Yin*. International Journal of Nanomedicine, 2020, 15:3563-3576.
Anti-tumor outcome evaluation against non-small cell lung cancer in vitro and in vivo using PolyI:C as nucleic acid therapeutic agent. Yedan Wu, Wei Huang, Liqing Chen, Mingji Jin, Zhonggao Gao*, Changshan An*, Haixiang Lin.American Journal of Translational Research, 2019, 11(4): 1919-1937.
Improving the anti-keloid outcomes through liposomes loading paclitaxel–cholesterol complexes. Mengjiao Wang, Liqing Chen, Wei Huang, Mingji Jin, Qiming Wang, Zhonggao Gao*, Zhehu Jin*. International Journal of Nanomedicine, 2019,14:1385-1400.
Topical application of JAK1/JAK2 inhibitor momelotinib exhibits significant anti-Inflammatory responses in DNCB-induced atopic dermatitis model mice.Wenyu Jin, Wei Huang, Liqing Chen, Mingji Jin, Qiming Wang, Zhonggao Gao*, Zhehu Jin*. International Journal of Molecular Sciences, 2018, 19(12), 3973.
Hybrid polymeric micelles based on bioactive polypeptides as pH-responsive delivery systems against melanoma. Qiming Wang, Zhonggao Gao*, Shan Liu, Bo Fan, Lin Kang, Wei Huang, Mingji Jin. Biomaterials, 2014, 35(25):7008-7021.